Adaptation by Loss of Heterozygosity in Saccharomyces cerevisiae Clones Under Divergent Selection.

TY, James; LA, Michelotti; AD, Glasco; RA, Clemons; RA, Powers; ES, James; DR, Simmons; F, Bai; S, Ge

doi:10.1534/genetics.119.302411

Public

Adaptation by Loss of Heterozygosity in Saccharomyces cerevisiae Clones Under Divergent Selection.

Shared by NobleBlocks on Aug 1, 2019 • 12:00 AM UTC

Authors:

James TY

Michelotti LA

Glasco AD

Abstract

Loss of heterozygosity (LOH) is observed during vegetative growth and reproduction of diploid genotypes through mitotic crossovers, aneuploidy caused by nondisjunction, and gene conversion. We aimed to test the role that LOH plays during adaptation of two highly heterozygous Saccharomyces cerevis...

Subject

Saccharomyces cerevisiae

Gene Conversion

Experimental Evolution

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