Tissue-resident memory CD8&lt;sup&gt;+&lt;/sup&gt; T cells amplify anti-tumor immunity by triggering antigen spreading through dendritic cells.

E, Menares; F, Gálvez-Cancino; P, Cáceres-Morgado; E, Ghorani; E, López; X, Díaz; J, Saavedra-Almarza; DA, Figueroa; E, Roa; SA, Quezada; A, Lladser

doi:10.1038/s41467-019-12319-x

Public

Tissue-resident memory CD8<sup>+</sup> T cells amplify anti-tumor immunity by triggering antigen spreading through dendritic cells.

Published in Nature communications • Sep 27, 2019

Authors:

Menares E

Gálvez-Cancino F

Cáceres-Morgado P

Abstract

Tissue-resident memory CD8<sup>+</sup> T (Trm) cells mediate potent local innate and adaptive immune responses and play a central role against solid tumors. However, whether Trm cells cross-talk with dendritic cells (DCs) to support anti-tumor immunity remains unclear. Here we show that antigen-spec...

View

Open Access

Generate AI Take for this paper

Highlights, strengths & weaknesses, commercial applications, and societal impact — written for this paper on demand.

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!