Skeletal stem cell-mediated suppression on inflammatory osteoclastogenesis occurs via concerted action of cell adhesion molecules and osteoprotegerin.

X, Li; L, Ding; YX, Wang; ZL, Li; Q, Wang; ZD, Zhao; S, Zhao; H, Wang; CT, Wu; N, Mao; H, Zhu

doi:10.1002/sctm.19-0300

Public

Skeletal stem cell-mediated suppression on inflammatory osteoclastogenesis occurs via concerted action of cell adhesion molecules and osteoprotegerin.

Shared by NobleBlocks on Nov 27, 2019 • 12:00 AM UTC

Authors:

Li X

Ding L

Wang YX

Abstract

In the current study, we investigated how skeletal stem cells (SSCs) modulate inflammatory osteoclast (OC) formation and bone resorption. Notably, we found that intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and osteoprotegerin (OPG) play a synergistic role i...

Subject

Cell adhesion molecules

Osteoprotegerin

Skeletal Stem Cells

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!