BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design.

C, Covián; A, Fernández-Fierro; A, Retamal-Díaz; FE, Díaz; AE, Vasquez; MK, Lay; CA, Riedel; PA, González; SM, Bueno; AM, Kalergis

doi:10.3389/fimmu.2019.02806

Public

BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design.

Published in Frontiers in immunology • Nov 29, 2019

Authors:

Covián C

Fernández-Fierro A

Retamal-Díaz A

Abstract

The Bacillus Calmette-Guérin (BCG) is a live attenuated tuberculosis vaccine that has the ability to induce non-specific cross-protection against pathogens that might be unrelated to the target disease. Vaccination with BCG reduces mortality in newborns and induces an improved innate immune response...

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Open Access

Subject

Vaccine

BCG

innate immunity

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