Extracellular vesicles of carcinoma-associated fibroblasts creates a pre-metastatic niche in the lung through activating fibroblasts.

J, Kong; H, Tian; F, Zhang; Z, Zhang; J, Li; X, Liu; X, Li; J, Liu; X, Li; D, Jin; X, Yang; B, Sun; T, Guo; Y, Luo; Y, Lu; B, Lin; T, Liu

doi:10.1186/s12943-019-1101-4

Public

Extracellular vesicles of carcinoma-associated fibroblasts creates a pre-metastatic niche in the lung through activating fibroblasts.

Shared by NobleBlocks on Dec 3, 2019 • 12:00 AM UTC

Authors:

Kong J

Tian H

Zhang F

Abstract

<h4>Objectives</h4>Carcinoma-associated fibroblasts (CAFs) have been known to promote cancer progression by modifying the primary tumor microenvironment. We aimed to elucidate the intercellular communication between CAFs and secondary organs in salivary adenoid cystic carcinoma (SACC) metastasis.<h4...

Subject

lung metastasis

Extracellular Vesicles

Pre-metastatic Niche

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