Synthesis of Cyclobutane-Fused Tetracyclic Scaffolds via Visible-Light Photocatalysis for Building Molecular Complexity.

MS, Oderinde; E, Mao; A, Ramirez; J, Pawluczyk; C, Jorge; LAM, Cornelius; J, Kempson; M, Vetrichelvan; M, Pitchai; A, Gupta; AK, Gupta; NA, Meanwell; A, Mathur; TGM, Dhar

doi:10.1021/jacs.9b12129

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Synthesis of Cyclobutane-Fused Tetracyclic Scaffolds via Visible-Light Photocatalysis for Building Molecular Complexity.

Shared by NobleBlocks on Jan 22, 2020 • 12:00 AM UTC

Authors:

Oderinde MS

Mao E

Ramirez A

Abstract

We describe the synthesis through visible-light photocatalysis of novel functionalized tetracyclic scaffolds that incorporate a fused azabicyclo[3.2.0]heptan-2-one motif, which are structurally interesting cores with potential in natural product synthesis and drug discovery. The synthetic approach i...

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