Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice

Kimura, Ikuo; Miyamoto, Junki; Ohue-Kitano, Ryuji; Watanabe, Keita; Yamada, Takahiro; Onuki, Masayoshi; Aoki, Ryo; Isobe, Yosuke; Kashihara, Daiji; Inoue, Daisuke; Inaba, Akihiko; Takamura, Yuta; Taira, Satsuki; Kumaki, Shunsuke; Watanabe, Masaki; Ito, Masato; Nakagawa, Fumiyuki; Irie, Junichiro; Kakuta, Hiroki; Shinohara, Masakazu; Iwatsuki, Ken; Tsujimoto, Gozoh; Ohno, Hiroaki; Arita, Makoto; Itoh, Hiroshi; Hase, Koji

doi:10.1126/science.aaw8429

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Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice

Shared by NobleBlocks on Feb 28, 2020 • 12:00 AM UTC

Authors:

Ikuo Kimura

Junki Miyamoto

Ryuji Ohue-Kitano

Abstract

Mouse mothers transfer metabolic mode Obesity and metabolic diseases tend to go together, and humans who become obese are also prone to type 2 diabetes and cardiovascular problems. Starting with the observation that offspring of germ-free mice tended to become obese on high-fat diets, Kimura et al. ...

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