A Proof-of-Concept Study on the Therapeutic Potential of Au Nanoparticles Radiolabeled with the Alpha-Emitter Actinium-225.

EA, Salvanou; D, Stellas; C, Tsoukalas; B, Mavroidi; M, Paravatou-Petsotas; N, Kalogeropoulos; S, Xanthopoulos; F, Denat; G, Laurent; R, Bazzi; S, Roux; P, Bouziotis

doi:10.3390/pharmaceutics12020188

Public

A Proof-of-Concept Study on the Therapeutic Potential of Au Nanoparticles Radiolabeled with the Alpha-Emitter Actinium-225.

Shared by NobleBlocks on Feb 21, 2020 • 12:00 AM UTC

Authors:

Salvanou EA

Stellas D

Tsoukalas C

Abstract

Actinium-225 (<sup>225</sup>Ac) is receiving increased attention for its application in targeted radionuclide therapy, due to the short range of its emitted alpha particles in conjunction with their high linear energy transfer, which lead to the eradication of tumor cells while sparing neighboring h...

Subject

Cancer therapy

Brachytherapy

Radiolabeling

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