Non-active antibiotic and bacteriophage synergism to successfully treat recurrent urinary tract infection caused by extensively drug-resistant Klebsiella pneumoniae.

J, Bao; N, Wu; Y, Zeng; L, Chen; L, Li; L, Yang; Y, Zhang; M, Guo; L, Li; J, Li; D, Tan; M, Cheng; J, Gu; J, Qin; J, Liu; S, Li; G, Pan; X, Jin; B, Yao; X, Guo; T, Zhu; S, Le

doi:10.1080/22221751.2020.1747950

Public

Non-active antibiotic and bacteriophage synergism to successfully treat recurrent urinary tract infection caused by extensively drug-resistant Klebsiella pneumoniae.

Shared by NobleBlocks on Dec 1, 2020 • 12:00 AM UTC

Authors:

Bao J

Wu N

Zeng Y

Abstract

We report a case of a 63-year-old female patient who developed a recurrent urinary tract infection (UTI) with extensively drug-resistant Klebsiella pneumoniae (ERKp). In the initial two rounds of phage therapy, phage resistant mutants developed within days. Although ERKp strains were complete...

Subject

Bacteriophage

Antibiotic Resistance

Urinary tract infection

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