Risk of colorectal cancer associated with BRCA1 and/or BRCA2 mutation carriers: systematic review and meta-analysis

M Cullinane, C; Creavin, B; P O'Connell, E; Kelly, L; J O'Sullivan, M; A Corrigan, M; P Redmond, H

doi:10.1002/bjs.11603

Public

Risk of colorectal cancer associated with BRCA1 and/or BRCA2 mutation carriers: systematic review and meta-analysis

Shared by NobleBlocks on Apr 16, 2020 • 12:00 AM UTC

Authors:

C M Cullinane

B Creavin

E P O'Connell

Abstract

Abstract Background Carriers of the BRCA1 and/or BRCA2 mutation incur a lifetime risk of up to 85 per cent for breast cancer, and between 20 and 40 per cent for ovarian cancer. Efforts to estimate the lifetime risk of developing colorectal cancer for BRCA mutation carriers have produced conflicting ...

Risk of colorectal cancer associated with <i>BRCA1</i> and/or <i>BRCA2</i> mutation carriers: systematic review and meta-analysis

Abstract

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