Palladium and Copper Catalyzed Sonogashira cross Coupling an Excellent Methodology for C-C Bond Formation over 17 Years: A Review

Kanwal, Iram; Mujahid, Aqsa; Rasool, Nasır; Rızwan, Komal; Malik, Ayesha; Ahmad, Gulraız; Adnan Alı Shah, Syed; Rashid, Umer; Mad Nasir, Nadiah

doi:10.3390/catal10040443

Public

Palladium and Copper Catalyzed Sonogashira cross Coupling an Excellent Methodology for C-C Bond Formation over 17 Years: A Review

Shared by NobleBlocks on Apr 20, 2020 • 12:00 AM UTC

Authors:

Iram Kanwal

Aqsa Mujahid

Nasır Rasool

Abstract

Sonogashira coupling involves coupling of vinyl/aryl halides with terminal acetylenes catalyzed by transition metals, especially palladium and copper. This is a well known reaction in organic synthesis and plays a role in sp2-sp C-C bond formations. This cross coupling was used in synthesis of natur...

Subject

Sonogashira coupling

Palladium

Catalysis

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