A case study of 10 patients administered HBOC-201 in high doses over a prolonged period: outcomes during severe anemia when transfusion is not an option.

M, Zumberg; J, Gorlin; EA, Griffiths; G, Schwartz; BS, Fletcher; K, Walsh; KH, Dao; A, Vansandt; M, Lynn; A, Shander

doi:10.1111/trf.15778

Public

A case study of 10 patients administered HBOC-201 in high doses over a prolonged period: outcomes during severe anemia when transfusion is not an option.

Shared by NobleBlocks on May 1, 2020 • 12:00 AM UTC

Authors:

Zumberg M

Gorlin J

Griffiths EA

Abstract

<h4>Background</h4>Hemoglobin-Based Oxygen Carriers (HBOCs) can act as an "oxygen bridge" in acute severe anemia when transfusion is indicated, but not possible. We present data on 10 Expanded Access (EA) patients treated with high cumulative doses of Hemopure (HBOC-201), to assess the ability of HB...

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