The Pan-Immune-Inflammation Value is a new prognostic biomarker in metastatic colorectal cancer: results from a pooled-analysis of the Valentino and TRIBE first-line trials

Fucà, Giovanni; Guarini, Vincenzo; Antoniotti, Carlotta; Morano, Federica; Moretto, Roberto; Corallo, Salvatore; Marmorino, Federica; Lonardi, Sara; Rimassa, Lorenza; Sartore-Bianchi, Andrea; Borelli, Beatrice; Tampellini, Marco; Bustreo, Sara; Claravezza, Matteo; Boccaccino, Alessandra; Murialdo, Roberto; Zaniboni, Alberto; Tomasello, Gianluca; Loupakis, Fotios; Adamo, Vincenzo; Tonini, Giuseppe; Cortesi, Enrico; de Braud, Filippo; Cremolini, Chiara; Pietrantonio, Filippo

doi:10.1038/s41416-020-0894-7

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The Pan-Immune-Inflammation Value is a new prognostic biomarker in metastatic colorectal cancer: results from a pooled-analysis of the Valentino and TRIBE first-line trials

Shared by NobleBlocks on May 19, 2020 • 12:00 AM UTC

Authors:

Giovanni Fucà

Vincenzo Guarini

Carlotta Antoniotti

Abstract

Abstract Background Immune-inflammatory biomarkers (IIBs) showed a prognostic relevance in patients with metastatic CRC (mCRC). We aimed at evaluating the prognostic power of a new comprehensive biomarker, the Pan-Immune-Inflammation Value (PIV), in patients with mCRC receiving first-line therapy. M...

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