Synthesis, Docking Study and Biological Activities Evaluation of 1‐Amidoalkyl‐2‐naphthol Derivatives as Dual Inhibitors of Cholinesterase and α‐Glucosidase

Boudebbous, Khawla; Boulebd, Houssem; Bensouıcı, Chawki; Harakat, Dominique; Boulcina, Raouf; Debache, Abdelmadjid

doi:10.1002/slct.202000558

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Synthesis, Docking Study and Biological Activities Evaluation of 1‐Amidoalkyl‐2‐naphthol Derivatives as Dual Inhibitors of Cholinesterase and α‐Glucosidase

Shared by NobleBlocks on May 15, 2020 • 12:00 AM UTC

Authors:

Khawla Boudebbous

Houssem Boulebd

Chawki Bensouıcı

Abstract

Abstract An efficient green synthesis of 1‐amidoalkyl‐2‐naphthol derivatives 4 a‐s has been developed, employing phenylboronic acid, by a three component one‐pot condensation reaction of 2‐naphthol, a wide range of functionalized aromatic aldehydes and acetamide, or acrylamide under solvent‐free con...

Subject

Chemistry

Acetamide

Butyrylcholinesterase

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