Semaphorin 3B-associated membranous nephropathy is a distinct type of disease predominantly present in pediatric patients.

S, Sethi; H, Debiec; B, Madden; M, Vivarelli; MC, Charlesworth; A, Ravindran; L, Gross; T, Ulinski; D, Buob; CL, Tran; F, Emma; F, Diomedi-Camassei; FC, Fervenza; P, Ronco

doi:10.1016/j.kint.2020.05.030

Public

Semaphorin 3B-associated membranous nephropathy is a distinct type of disease predominantly present in pediatric patients.

Shared by NobleBlocks on Jun 11, 2020 • 12:00 AM UTC

Authors:

Sethi S

Debiec H

Madden B

Abstract

Membranous nephropathy results from subepithelial antigen-antibody complex deposition along the glomerular basement membrane. Although PLA2R, THSD7A, and NELL-1 account for a majority (about 80%) of the target antigens, the target antigen in the remaining cases is not known. Using laser microdissect...

Subject

Mass spectrometry

Membranous Nephropathy

Kidney Biopsy

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