Multikilogram per Hour Continuous Photochemical Benzylic Brominations Applying a Smart Dimensioning Scale-up Strategy

Steiner, Alexander; M. C. Roth, Philippe; Josef Strauß, Franz; Gauron, Guillaume; Tekautz, Günter; Winter, Marc; D. Williams, Jason; Oliver Kappe, C.

doi:10.1021/acs.oprd.0c00239

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Multikilogram per Hour Continuous Photochemical Benzylic Brominations Applying a Smart Dimensioning Scale-up Strategy

Shared by NobleBlocks on Jun 15, 2020 • 12:00 AM UTC

Authors:

Alexander Steiner

Philippe M. C. Roth

Franz Josef Strauß

Abstract

Although continuous flow technology can facilitate the scale-up of photochemical processes it is not yet routinely implemented on production scale in the fine chemical industries. This can be attributed to additional challenges compared to thermal processes, mostly in the homogeneous irradiation of ...

Subject

Yield (engineering)

Flow chemistry

Residence time (fluid dynamics)

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