Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized With Coronavirus Disease 2019: The GRECCO-19 Randomized Clinical Trial.

SG, Deftereos; G, Giannopoulos; DA, Vrachatis; GD, Siasos; SG, Giotaki; P, Gargalianos; S, Metallidis; G, Sianos; S, Baltagiannis; P, Panagopoulos; K, Dolianitis; E, Randou; K, Syrigos; A, Kotanidou; NG, Koulouris; H, Milionis; N, Sipsas; C, Gogos; G, Tsoukalas; CD, Olympios; E, Tsagalou; I, Migdalis; S, Gerakari; C, Angelidis; D, Alexopoulos; P, Davlouros; G, Hahalis; I, Kanonidis; D, Katritsis; T, Kolettis; AS, Manolis; L, Michalis; KK, Naka; VN, Pyrgakis; KP, Toutouzas; F, Triposkiadis; K, Tsioufis; E, Vavouranakis; L, Martinèz-Dolz; B, Reimers; GG, Stefanini; M, Cleman; J, Goudevenos; S, Tsiodras; D, Tousoulis; E, Iliodromitis; R, Mehran; G, Dangas; C, Stefanadis

doi:10.1001/jamanetworkopen.2020.13136

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Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized With Coronavirus Disease 2019: The GRECCO-19 Randomized Clinical Trial.

Shared by NobleBlocks on Jun 1, 2020 • 12:00 AM UTC

Authors:

Deftereos SG

Giannopoulos G

Vrachatis DA

Abstract

<h4>Importance</h4>Severe acute respiratory syndrome coronavirus 2 infection has evolved into a global pandemic. Low-dose colchicine combines anti-inflammatory action with a favorable safety profile.<h4>Objective</h4>To evaluate the effect of treatment with colchicine on cardiac and inflammatory bio...

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