Trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer and brain metastases: exploratory final analysis of cohort 1 from KAMILLA, a single-arm phase IIIb clinical trial<sup>☆</sup>.

F, Montemurro; S, Delaloge; CH, Barrios; R, Wuerstlein; A, Anton; E, Brain; T, Hatschek; CM, Kelly; C, Peña-Murillo; M, Yilmaz; M, Donica; P, Ellis

doi:10.1016/j.annonc.2020.06.020

Public

Trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer and brain metastases: exploratory final analysis of cohort 1 from KAMILLA, a single-arm phase IIIb clinical trial<sup>☆</sup>.

Shared by NobleBlocks on Jul 5, 2020 • 12:00 AM UTC

Authors:

Montemurro F

Delaloge S

Barrios CH

Abstract

<h4>Background</h4>Patients with brain metastases (BM) from human epidermal growth factor receptor 2 (HER2)-positive breast cancer represent a difficult-to-treat population. Trastuzumab emtansine (T-DM1) has shown potential activity in this subset of patients in small clinical series.<h4>Patients an...

Subject

Metastatic breast cancer

Brain metastases

Trastuzumab Emtansine

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