Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials.

F, Pazan; M, Petrovic; A, Cherubini; G, Onder; AJ, Cruz-Jentoft; M, Denkinger; der Cammen TJM, van; JM, Stevenson; K, Ibrahim; C, Rajkumar; MS, Bakken; JP, Baeyens; P, Crome; T, Frühwald; P, Gallaghar; A, Guðmundsson; W, Knol; D, O'Mahony; A, Pilotto; E, Rönnemaa; JA, Serra-Rexach; G, Soulis; Marum RJ, van; G, Ziere; A, Mair; H, Burkhardt; A, Neumann-Podczaska; K, Wieczorowska-Tobis; MA, Fernandes; H, Gruner; D, Dallmeier; JB, Beuscart; der Velde N, van; M, Wehling

doi:10.1007/s00228-020-02951-8

Public

Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials.

Shared by NobleBlocks on Aug 7, 2020 • 12:00 AM UTC

Authors:

Pazan F

Petrovic M

Cherubini A

Abstract

<h4>Background</h4>Frailty and adverse drug effects are linked in the fact that polypharmacy is correlated with the severity of frailty; however, a causal relation has not been proven in older people with clinically manifest frailty.<h4>Methods</h4>A literature search was performed in Medline to det...

Subject

Frailty

Older People

Polypharmacy

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