Methylprednisolone as Adjunctive Therapy for Patients Hospitalized With Coronavirus Disease 2019 (COVID-19; Metcovid): A Randomized, Double-blind, Phase IIb, Placebo-controlled Trial.

CMP, Jeronimo; MEL, Farias; FFA, Val; VS, Sampaio; MAA, Alexandre; GC, Melo; IP, Safe; MGS, Borba; RLA, Netto; ABS, Maciel; JRS, Neto; LB, Oliveira; EFG, Figueiredo; Dinelly KM, Oliveira; Almeida Rodrigues MG, de; M, Brito; MPG, Mourão; João GA, Pivoto; LA, Hajjar; Q, Bassat; GAS, Romero; FG, Naveca; HL, Vasconcelos; Araújo Tavares M, de; JD, Brito-Sousa; FTM, Costa; ML, Nogueira; DC, Baía-da-Silva; MS, Xavier; WM, Monteiro; MVG, Lacerda

doi:10.1093/cid/ciaa1177

Public

Methylprednisolone as Adjunctive Therapy for Patients Hospitalized With Coronavirus Disease 2019 (COVID-19; Metcovid): A Randomized, Double-blind, Phase IIb, Placebo-controlled Trial.

Shared by NobleBlocks on May 1, 2021 • 12:00 AM UTC

Authors:

Jeronimo CMP

Farias MEL

Val FFA

Abstract

<h4>Background</h4>Steroid use for coronavirus disease 2019 (COVID-19) is based on the possible role of these drugs in mitigating the inflammatory response, mainly in the lungs, triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This study aimed to evaluate the efficacy of me...

Subject

Inflammation

Brazil

Coronavirus

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