КОМПЛЕМЕНТ ПРИ ПАТОЛОГИЯХ, ВОЗМОЖНОСТЬ КОРРЕКЦИИ С ПОМОЩЬЮ НОВОГО ГУМАНИЗИРОВАННОГО АНТИТЕЛА, БЛОКИРУЮЩЕГО АЛЬТЕРНАТИВНЫЙ ПУТЬ

Two monoclonal antibodies were developed and were shown to block the complement system alternative pathway (AP) activation at the stage of assembly and activation of C3 convertase. The humanized antibody hC34 specific to a binding site on α’2 determinant of С3с fragment inhibited in vitro the human ... View More