Urine DNA methylation assay enables early detection and recurrence monitoring for bladder cancer.

Chen, Xu; Zhang, Jingtong; Ruan, W.; Huang, Ming; Wang, Chanjuan; Wang, Hong; Jiang, Zeyu; Wang, Shaogang; Liu, Zheng; Liu, Chunxiao; Tan, W.; Yang, Jin; Chen, Jiaxin; Chen, Zhiwei; Li, Xia; Zhang, Xiaoyu; Xu, Peng; Chen, Lin; Xie, Ruihui; Zhou, Qianghua; Xu, Shizhong; Irwin, D.; Fan, Jianbing; Huang, Jian; Lin, Tianxin

doi:10.1172/JCI139597

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Urine DNA methylation assay enables early detection and recurrence monitoring for bladder cancer.

Shared by NobleBlocks on Aug 20, 2020 • 12:00 AM UTC

Authors:

Xu Chen

Jingtong Zhang

W. Ruan

Abstract

BACKGROUND Current methods for the detection and surveillance of bladder cancer (BCa) are often invasive and/or possess suboptimal sensitivity and specificity, especially in early stage, minimal, residual tumors. METHODS We developed a novel method for the detection of urine tumor DNA Methylation ...

Subject

Medicine

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