IRF1 Promotes the Innate Immune Response to Viral Infection by Enhancing the Activation of IRF3.

J, Wang; H, Li; B, Xue; R, Deng; X, Huang; Y, Xu; S, Chen; R, Tian; X, Wang; Z, Xun; M, Sang; H, Zhu

doi:10.1128/jvi.01231-20

Public

IRF1 Promotes the Innate Immune Response to Viral Infection by Enhancing the Activation of IRF3.

Shared by NobleBlocks on Oct 27, 2020 • 12:00 AM UTC

Authors:

Wang J

Li H

Xue B

Abstract

Innate immunity is an essential way for host cells to resist viral infection through the production of interferons (IFNs) and proinflammatory cytokines. Interferon regulatory factor 3 (IRF3) plays a critical role in the innate immune response to viral infection. However, the role of IRF1 in innate i...

Subject

Virus

Interferon

innate immunity

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