Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19: A Randomized Clinical Trial.

Dequin, P.; Heming, N.; Meziani, F.; Plantefeve, G.; Voiriot, G.; Badie, J.; François, B.; Aubron, C.; Ricard, J.; Ehrmann, S.; Jouan, Y.; Guillon, A.; Leclerc, M.; Coffre, Carine; Bourgoin, H.; Lengellé, C.; Caille-Fénérol, Caroline; Tavernier, E.; Zohar, S.; Giraudeau, B.; Annane, D.; Le Gouge, A.

doi:10.1001/jama.2020.16761

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Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19: A Randomized Clinical Trial.

Shared by NobleBlocks on Oct 6, 2020 • 12:00 AM UTC

Authors:

Pierre-François Dequin

Nicholas Heming

Ferhat Meziani

Abstract

Importance: Coronavirus disease 2019 (COVID-19) is associated with severe lung damage. Corticosteroids are a possible therapeutic option. Objective: To determine the effect of hydrocortisone on treatment failure on day 21 in critically ill patients with severe acute respiratory syndrome coronavirus ...

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