Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

Cantuti-Castelvetri, Ludovico; Ojha, Ravi; D Pedro, Liliana; Djannatian, Minou; Franz, J.; Kuivanen, S.; van der Meer, F.; Kallio, Katri; Kaya, Tugberk; Anastasina, Maria; Smura, T.; Levanov, L.; Szirovicza, Leonóra; Tobi, Allan; Kallio-kokko, H.; Österlund, Pamela; Joensuu, Merja; Meunier, F.; Butcher, S.; Winkler, M.; Mollenhauer, B.; Helenius, A.; Gokce, O.; Teesalu, T.; Hepojoki, J.; Vapalahti, O.; Stadelmann, C.; Balistreri, G.; Simons, M.

doi:10.1126/science.abd2985

Public

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity.

Shared by NobleBlocks on Oct 20, 2020 • 12:00 AM UTC

Authors:

Cantuti-Castelvetri L

Ojha R

Pedro LD

Abstract

The causative agent of coronavirus disease 2019 (COVID-19) is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). For many viruses, tissue tropism is determined by the availability of virus receptors and entry cofactors on the surface of host cells. In this study, we found that neuropi...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!