TM4SF1 promotes EMT and cancer stemness via the Wnt/β-catenin/SOX2 pathway in colorectal cancer

Tang, Qiang; Chen, Jinhuang; Di, Ziyang; Yuan, Wenzheng; Zhou, Zili; Liu, Zhengyi; Han, Shengbo; Liu, Yanwei; Ying, Guoguang; Shu, Xiaogang; Di, Maojun

doi:10.1186/s13046-020-01690-z

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TM4SF1 promotes EMT and cancer stemness via the Wnt/β-catenin/SOX2 pathway in colorectal cancer

Shared by NobleBlocks on Nov 5, 2020 • 12:00 AM UTC

Authors:

Qiang Tang

Jinhuang Chen

Ziyang Di

Abstract

Abstract Background Transmembrane 4 L six family member 1 (TM4SF1) is upregulated in several epithelial cancers and is closely associated with poor prognosis. However, the role of TM4SF1 and its potential mechanism in colorectal cancer (CRC) remain elusive. Methods We investigated the expression of ...

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