The SARS-CoV-2 RNA-protein interactome in infected human cells.

N, Schmidt; CA, Lareau; H, Keshishian; S, Ganskih; C, Schneider; T, Hennig; R, Melanson; S, Werner; Y, Wei; M, Zimmer; J, Ade; L, Kirschner; S, Zielinski; L, Dölken; ES, Lander; N, Caliskan; U, Fischer; J, Vogel; SA, Carr; J, Bodem; M, Munschauer

doi:10.1038/s41564-020-00846-z

Public

The SARS-CoV-2 RNA-protein interactome in infected human cells.

Shared by NobleBlocks on Dec 21, 2020 • 12:00 AM UTC

Authors:

Schmidt N

Lareau CA

Keshishian H

Abstract

Characterizing the interactions that SARS-CoV-2 viral RNAs make with host cell proteins during infection can improve our understanding of viral RNA functions and the host innate immune response. Using RNA antisense purification and mass spectrometry, we identified up to 104 human proteins that direc...

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