Siglec15 shapes a non-inflamed tumor microenvironment and predicts the molecular subtype in bladder cancer.

J, Hu; A, Yu; B, Othmane; D, Qiu; H, Li; C, Li; P, Liu; W, Ren; M, Chen; G, Gong; X, Guo; H, Zhang; J, Chen; X, Zu

doi:10.7150/thno.53649

Public

Siglec15 shapes a non-inflamed tumor microenvironment and predicts the molecular subtype in bladder cancer.

Shared by NobleBlocks on Jan 1, 2021 • 12:00 AM UTC

Authors:

Hu J

Yu A

Othmane B

Abstract

<b>Rationale:</b> Siglec15 is an emerging target for normalization cancer immunotherapy. However, pan-cancer anti-Siglec15 treatment is not yet validated and the potential role of Siglec15 in bladder cancer (BLCA) remains elusive. <b>Methods:</b> We comprehensively evaluated the expression pattern a...

Subject

Immunotherapy

Bladder cancer

Tumor Microenvironment

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