Berberine Protects Against NLRP3 Inflammasome via Ameliorating Autophagic Impairment in MPTP-Induced Parkinson's Disease Model.

S, Huang; H, Liu; Y, Lin; M, Liu; Y, Li; H, Mao; Z, Zhang; Y, Zhang; P, Ye; L, Ding; Z, Zhu; X, Yang; C, Chen; X, Zhu; X, Huang; W, Guo; P, Xu; L, Lu

doi:10.3389/fphar.2020.618787

Public

Berberine Protects Against NLRP3 Inflammasome via Ameliorating Autophagic Impairment in MPTP-Induced Parkinson's Disease Model.

Shared by NobleBlocks on Jan 27, 2021 • 12:00 AM UTC

Authors:

Huang S

Liu H

Lin Y

Abstract

The NLR family pyrin domain containing 3 (NLRP3) inflammasome was reported to be regulated by autophagy and activated during inflammatory procession of Parkinson's disease (PD). Berberine (BBR) is well-studied to play an important role in promoting anti-inflammatory response to mediate the autophagy...

Subject

Berberine

Autophagy

neuroinflammation

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