Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity

Rubino, Domenica; Abrahamsson, Niclas; Davies, Melanie; Hesse, Dan; L. Greenway, Frank; Jensen, Camilla; Lingvay, Ildiko; Mosenzon, Ofri; Rosenstock, Julio; A. Rubio, Miguel; Rudofsky, Gottfried; Tadayon, Sayeh; A. Wadden, Thomas; Dicker, Dror; 4 Investigators, STEP; Friberg, Mette; Sjödin, Anders; Dicker, Dror; Segal, Gabriella; Mosenzon, Ofri; Sabbah, Muhammad; Sofer, Yael; Vishlitzky, Victor; W. Meesters, Eelco; Serlie, Mirelle; van Bon, Arianne; Cardoso, Helena; Freitas, Paula; Carneiro de Melo, Pedro; Monteiro, Margarida; Monteiro, Mariana; Rodrigues, Dírcea; Badat, Aysha; Joshi, Pankaj; Latiff, Gulam; A. Mitha, Essack; H. Snyman, Hans; van Nieuwenhuizen, Elane; González Albarrán, Olga; Caixas, Assumpta; de al Cuesta, Carmen; Pablo Garcia Luna, Pedro; Morales Portillo, Cristobal; Mezquita Raya, Pedro; Angel Rubio, Miguel; Abrahamsson, Niclas; Hoffstedt, Johan; von Wowern, Fredrik; Uddman, Erik; Bach-Kliegel, Birgit; Beuschlein, Felix; Bilz, Stefan; Golay, Alain; Rudofsky, Gottfried; Strey, Christopher; Fadieienko, Galyna; Kosei, Nataliia; Tatarchuk, Tetiana; Velychko, Valentyna; Zinych, Olesya; L. Aronoff, Stephen; E. Bays, Harold; P. Brockmyre, Andrew; S. Call, Robert; Crump, Charles; V. Desouza, Cyrus; Espinosa, Valerie; L. Free, Almena; H. Gandy, Winston; A. Geller, Steven; M. Gottschlich, Gregory; L. Greenway, Frank; Han-Conrad, Laurie; Harper, Wayne; Herman, Lee; Hewitt, Mitzie; Hollander, Priscilla; R. Kaster, Steven; Manessis, Anastasios; A. Martin, Frederick; E. McNeill, Robert; V. Murray, Alexander; C. Norwood, Paul; C.H. Reed, John; Rosenstock, Julio; M. Rubino, Domenica; J. Schear, Martin; L. Warren, Mark

doi:10.1001/jama.2021.3224

Public

Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity

Shared by NobleBlocks on Apr 13, 2021 • 12:00 AM UTC

Authors:

Domenica Rubino

Niclas Abrahamsson

Melanie Davies

Abstract

Importance The effect of continuing vs withdrawing treatment with semaglutide, a glucagon-like peptide 1 receptor agonist, on weight loss maintenance in people with overweight or obesity is unknown. Objective To compare continued once-weekly treatment with subcutaneous semaglutide, 2.4 mg, with swit...

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