Large scale association analysis identifies three susceptibility loci for coronary artery disease.

Saade, Stephanie; Cazier, Jean-Baptiste; Ghassibe-Sabbagh, Michella; Youhanna, Sonia; A Badro, Danielle; Kamatani, Yoichiro; Hager, Jörg; S Yeretzian, Joumana; El-Khazen, Georges; Haber, Marc; K Salloum, Angelique; Douaihy, Bouchra; Othman, Raed; Shasha, Nabil; Kabbani, Samer; El Bayeh, Hamid; Chammas, Elie; Farrall, Martin; Gauguier, Dominique; E Platt, Daniel; A Zalloua, Pierre; consortium, FGENTCARD

doi:10.1371/journal.pone.0029427

Public

Large scale association analysis identifies three susceptibility loci for coronary artery disease.

Shared by NobleBlocks on Jan 1, 2011 • 12:00 AM UTC

Authors:

Stephanie Saade

Jean-Baptiste Cazier

Michella Ghassibe-Sabbagh

Abstract

Genome wide association studies (GWAS) and their replications that have associated DNA variants with myocardial infarction (MI) and/or coronary artery disease (CAD) are predominantly based on populations of European or Eastern Asian descent. Replication of the most significantly associated polymorph...

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