Complement Overactivation and Consumption Predicts In-Hospital Mortality in SARS-CoV-2 Infection.

G, Sinkovits; B, Mező; M, Réti; V, Müller; Z, Iványi; J, Gál; L, Gopcsa; P, Reményi; B, Szathmáry; B, Lakatos; J, Szlávik; I, Bobek; ZZ, Prohászka; Z, Förhécz; D, Csuka; L, Hurler; E, Kajdácsi; L, Cervenak; P, Kiszel; T, Masszi; I, Vályi-Nagy; Z, Prohászka

doi:10.3389/fimmu.2021.663187

Public

Complement Overactivation and Consumption Predicts In-Hospital Mortality in SARS-CoV-2 Infection.

Shared by NobleBlocks on Mar 25, 2021 • 12:00 AM UTC

Authors:

Sinkovits G

Mező B

Réti M

Abstract

<h4>Objectives</h4>Uncontrolled thromboinflammation plays an important role in the pathogenesis of coronavirus disease (COVID-19) caused by SARS-CoV-2 virus. Complement was implicated as key contributor to this process, therefore we hypothesized that markers of the complement profile, indicative for...

Subject

Mortality

Complement system

Severity

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