Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.

C, Axfors; AM, Schmitt; P, Janiaud; Hooft J, Van't; S, Abd-Elsalam; EF, Abdo; BS, Abella; J, Akram; RK, Amaravadi; DC, Angus; YM, Arabi; S, Azhar; LR, Baden; AW, Baker; L, Belkhir; T, Benfield; MAH, Berrevoets; CP, Chen; TC, Chen; SH, Cheng; CY, Cheng; WS, Chung; YZ, Cohen; LN, Cowan; O, Dalgard; Almeida E Val FF, de; Lacerda MVG, de; Melo GC, de; L, Derde; V, Dubee; A, Elfakir; AC, Gordon; CM, Hernandez-Cardenas; T, Hills; AIM, Hoepelman; YW, Huang; B, Igau; R, Jin; F, Jurado-Camacho; KS, Khan; PG, Kremsner; B, Kreuels; CY, Kuo; T, Le; YC, Lin; WP, Lin; TH, Lin; MN, Lyngbakken; C, McArthur; BJ, McVerry; P, Meza-Meneses; WM, Monteiro; SC, Morpeth; A, Mourad; MJ, Mulligan; S, Murthy; S, Naggie; S, Narayanasamy; A, Nichol; LA, Novack; SM, O'Brien; NL, Okeke; L, Perez; R, Perez-Padilla; L, Perrin; A, Remigio-Luna; NE, Rivera-Martinez; FW, Rockhold; S, Rodriguez-Llamazares; R, Rolfe; R, Rosa; H, Røsjø; VS, Sampaio; TB, Seto; M, Shahzad; S, Soliman; JE, Stout; I, Thirion-Romero; AB, Troxel; TY, Tseng; NA, Turner; RJ, Ulrich; SR, Walsh; SA, Webb; JM, Weehuizen; M, Velinova; HL, Wong; R, Wrenn; FG, Zampieri; W, Zhong; D, Moher; SN, Goodman; JPA, Ioannidis; LG, Hemkens

doi:10.1038/s41467-021-22446-z

Public

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.

Shared by NobleBlocks on Apr 15, 2021 • 12:00 AM UTC

Authors:

Axfors C

Schmitt AM

Janiaud P

Abstract

Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate the effects of hydroxychloroquine and chloroquine on survival in COVID-19 from ...

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