Heteroleptic enantiopure Pd(<scp>ii</scp>)-complexes derived from halogen-substituted Schiff bases and 2-picolylamine: synthesis, experimental and computational characterization and investigation of the influence of chirality and halogen atoms on the anticancer activity

Kordestani, Nazanin; Amiri Rudbari, Hadi; Correia, Isabel; Valente, Andreia; Côrte-Real, Leonor; Khairul Islam, Mohammad; Micale, Nicola; D. Braun, Jason; E. Herbert, David; Tumanov, Nikolay; Wouters, Johan; Enamullah, Mohammed

doi:10.1039/d1nj01491a

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Heteroleptic enantiopure Pd(<scp>ii</scp>)-complexes derived from halogen-substituted Schiff bases and 2-picolylamine: synthesis, experimental and computational characterization and investigation of the influence of chirality and halogen atoms on the anticancer activity

Shared by NobleBlocks on Jan 1, 2021 • 12:00 AM UTC

Authors:

Nazanin Kordestani

Hadi Amiri Rudbari

Isabel Correia

Abstract

To investigate the effect of chirality and different halogen substituents on the anticancer activity, seven enantiomeric pairs of palladium complexes were synthesized and characterized.

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