A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing.

GKC, Dowsett; BYH, Lam; JA, Tadross; I, Cimino; D, Rimmington; AP, Coll; J, Polex-Wolf; LB, Knudsen; C, Pyke; GSH, Yeo

doi:10.1016/j.molmet.2021.101240

Public

A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing.

Shared by NobleBlocks on May 4, 2021 • 12:00 AM UTC

Authors:

Dowsett GKC

Lam BYH

Tadross JA

Abstract

<h4>Objective</h4>The area postrema (AP) and nucleus tractus solitarius (NTS) located in the hindbrain are key nuclei that sense and integrate peripheral nutritional signals and consequently regulate feeding behaviour. While single-cell transcriptomics have been used in mice to reveal the gene expre...

Subject

Obesity

Area postrema

Nucleus tractus solitarius

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