A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes.

T, Grancharova; KA, Gerbin; AB, Rosenberg; CM, Roco; JE, Arakaki; CM, DeLizo; SQ, Dinh; RM, Donovan-Maiye; M, Hirano; AM, Nelson; J, Tang; JA, Theriot; C, Yan; V, Menon; SP, Palecek; G, Seelig; RN, Gunawardane

doi:10.1038/s41598-021-94732-1

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A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes.

Shared by NobleBlocks on Aug 4, 2021 • 12:00 AM UTC

Authors:

Grancharova T

Gerbin KA

Rosenberg AB

Abstract

We performed a comprehensive analysis of the transcriptional changes occurring during human induced pluripotent stem cell (hiPSC) differentiation to cardiomyocytes. Using single cell RNA-seq, we sequenced > 20,000 single cells from 55 independent samples representing two differentiation protocols an...

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