Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis.

X, Zhang; L, Peng; Y, Luo; S, Zhang; Y, Pu; Y, Chen; W, Guo; J, Yao; M, Shao; W, Fan; Q, Cui; Y, Xi; Y, Sun; X, Niu; X, Zhao; L, Chen; Y, Wang; Y, Liu; X, Yang; C, Wang; C, Zhong; W, Tan; J, Wang; C, Wu; D, Lin

doi:10.1038/s41467-021-25539-x

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Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis.

Shared by NobleBlocks on Sep 6, 2021 • 12:00 AM UTC

Authors:

Zhang X

Peng L

Luo Y

Abstract

Esophageal squamous-cell carcinoma (ESCC), one of the most prevalent and lethal malignant disease, has a complex but unknown tumor ecosystem. Here, we investigate the composition of ESCC tumors based on 208,659 single-cell transcriptomes derived from 60 individuals. We identify 8 common expression p...

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