Comparative cellular analysis of motor cortex in human, marmoset and mouse.

TE, Bakken; NL, Jorstad; Q, Hu; BB, Lake; W, Tian; BE, Kalmbach; M, Crow; RD, Hodge; FM, Krienen; SA, Sorensen; J, Eggermont; Z, Yao; BD, Aevermann; AI, Aldridge; A, Bartlett; D, Bertagnolli; T, Casper; RG, Castanon; K, Crichton; TL, Daigle; R, Dalley; N, Dee; N, Dembrow; D, Diep; SL, Ding; W, Dong; R, Fang; S, Fischer; M, Goldman; J, Goldy; LT, Graybuck; BR, Herb; X, Hou; J, Kancherla; M, Kroll; K, Lathia; Lew B, van; YE, Li; CS, Liu; H, Liu; JD, Lucero; A, Mahurkar; D, McMillen; JA, Miller; M, Moussa; JR, Nery; PR, Nicovich; SY, Niu; J, Orvis; JK, Osteen; S, Owen; CR, Palmer; T, Pham; N, Plongthongkum; O, Poirion; NM, Reed; C, Rimorin; A, Rivkin; WJ, Romanow; AE, Sedeño-Cortés; K, Siletti; S, Somasundaram; J, Sulc; M, Tieu; A, Torkelson; H, Tung; X, Wang; F, Xie; AM, Yanny; R, Zhang; SA, Ament; MM, Behrens; HC, Bravo; J, Chun; A, Dobin; J, Gillis; R, Hertzano; PR, Hof; T, Höllt; GD, Horwitz; CD, Keene; PV, Kharchenko; AL, Ko; BP, Lelieveldt; C, Luo; EA, Mukamel; A, Pinto-Duarte; S, Preissl; A, Regev; B, Ren; RH, Scheuermann; K, Smith; WJ, Spain; OR, White; C, Koch; M, Hawrylycz; B, Tasic; EZ, Macosko; SA, McCarroll; JT, Ting; H, Zeng; K, Zhang; G, Feng; JR, Ecker; S, Linnarsson; ES, Lein

doi:10.1038/s41586-021-03465-8

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Comparative cellular analysis of motor cortex in human, marmoset and mouse.

Shared by NobleBlocks on Oct 6, 2021 • 12:00 AM UTC

Authors:

Bakken TE

Jorstad NL

Hu Q

Abstract

The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally conserved across mammals<sup>1</sup>. Here, using high-throughput transcriptomic and epigenomic profiling of more than 450,000 single nuclei in humans, marmoset monkeys and mice, we demonstrate a broadly ...

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