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РЕКОМБИНАНТНЫЙ ПНЕВМОЛИЗИН ВЫЗЫВАЕТ ОБРАЗОВАНИЕ АНТИТЕЛ И ЗАЩИЩАЕТ МЫШЕЙ ОТ ПНЕВМОКОККОВОЙ ИНФЕКЦИИ

Published in Российский иммунологический журнал • Aug 14, 2020
NobleIDNI1P63W17R06S35
Authors:
Д С Воробьев
,
Е. С. Петухова
,
А. В. Сидоров

Abstract

The obtained recombinant pneumolysin (rPLY) Streptococcus pneumoniae in atoxic form. The immunogenic and protective activity of rPLY was studied. It was shown that in the sera of mice after double injection of rPLY, the IgG titer increased by up to 32 times as compared with the sera of intact mice. ...

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