シタグリプチン(ジャヌビア,グラクティブ) (特集 インクレチン関連薬による糖尿病治療の新時代) -- (インクレチン関連薬の臨床)

Recently, we demonstrated that asymmetrical 18 base-paired double-strand oligonucleotides comprised of alternately combined 2'-O-methyl RNA and DNA, termed MED-siRNAs, show high RNase resistance, efficient cleavage of target mRNA, and the subsequent reduction of target protein expression. The 5'-ter... View More