Efficacy and safety of an innovative prolonged-release combination drug in patients with distal renal tubular acidosis: an open-label comparative trial versus standard of care treatments.

A, Bertholet-Thomas; C, Guittet; MA, Manso-Silván; A, Castang; V, Baudouin; M, Cailliez; Maio M, Di; O, Gillion-Boyer; E, Golubovic; J, Harambat; A, Klein; B, Knebelmann; F, Nobili; R, Novo; L, Podracka; G, Roussey-Kesler; C, Stylianou; LA, Granier

doi:10.1007/s00467-020-04693-2

Public

Efficacy and safety of an innovative prolonged-release combination drug in patients with distal renal tubular acidosis: an open-label comparative trial versus standard of care treatments.

Shared by NobleBlocks on Jul 26, 2020 • 12:00 AM UTC

Authors:

Bertholet-Thomas A

Guittet C

Manso-Silván MA

Abstract

<h4>Background</h4>Distal renal tubular acidosis (dRTA), due to impaired acid secretion in the urine, can lead to severe long-term consequences. Standard of care (SoC) oral alkalizers, requiring several daily intakes, are currently used to restore normal plasma bicarbonate levels. A new prolonged-re...

Subject

Palatability

Gastrointestinal Tolerability

Drta

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