Effects of Alirocumab on Triglyceride Metabolism: A Fat-Tolerance Test and Nuclear Magnetic Resonance Spectroscopy Study.

T, Metzner; DR, Leitner; K, Mellitzer; A, Beck; H, Sourij; T, Stojakovic; G, Reishofer; W, März; U, Landmesser; H, Scharnagl; H, Toplak; G, Silbernagel

doi:10.3390/biomedicines10010193

Public

Effects of Alirocumab on Triglyceride Metabolism: A Fat-Tolerance Test and Nuclear Magnetic Resonance Spectroscopy Study.

Shared by NobleBlocks on Jan 17, 2022 • 12:00 AM UTC

Authors:

Metzner T

Leitner DR

Mellitzer K

Abstract

<h4>Background</h4>PCSK9 antibodies strongly reduce LDL cholesterol. The effects of PCSK9 antibodies on triglyceride metabolism are less pronounced. The present study aimed to investigate in detail the effects of alirocumab on triglycerides, triglyceride-rich lipoproteins, and lipase regulators.<h4>...

Subject

Lipids

Nuclear magnetic resonance spectroscopy

Pcsk9

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