PharmVar GeneFocus: <i>CYP3A5</i>

Rodriguez‐Antona, Cristina; L. Savieo, Jessica; M. Lauschke, Volker; Sangkuhl, Katrin; I. Drögemöller, Britt; Wang, Danxin; H. N. van Schaik, Ron; A. Gilep, Andrei; P. Peter, Arul; C. Boone, Erin; E. Ramey, Bronwyn; E. Klein, Teri; Whirl‐Carrillo, Michelle; M. Pratt, Victoria; Gaedigk, Andrea

doi:10.1002/cpt.2563

Public

PharmVar GeneFocus: <i>CYP3A5</i>

Shared by NobleBlocks on Mar 28, 2022 • 12:00 AM UTC

Authors:

Cristina Rodriguez‐Antona

Jessica L. Savieo

Volker M. Lauschke

Abstract

The Pharmacogene Variation Consortium (PharmVar) catalogs star (*) allele nomenclature for the polymorphic human CYP3A5 gene. Genetic variation within the CYP3A5 gene locus impacts the metabolism of several clinically important drugs, including the immunosuppressants tacrolimus, sirolimus, cyclospor...

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