SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease

Alimoradi, Nahid; Sharqi, Moein; Firouzabadi, Dena; Moein Sadeghi, Mohammad; Mohammad Iman Moezzi, Seyed; Firouzabadi, Negar

doi:10.1186/s12985-022-01782-6

Public

SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease

Shared by NobleBlocks on Mar 19, 2022 • 12:00 AM UTC

Authors:

Nahid Alimoradi

Moein Sharqi

Dena Firouzabadi

Abstract

COVID-19 and the renin-angiotensin system (RAS) are linked by angiotensin-converting enzyme 2 (ACE2), a key enzyme in RAS that has been validated as a SARS-CoV-2 receptor. Functional ACE1/ACE2 gene polymorphisms may lead to the imbalance between ACE/ACE2 ratio and thus generating RAS imbalance that ...

Subject

Genotype

Angiotensin-converting enzyme 2

ARDS

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!