Anti-inflammatory effect of lentil hull (Lens culinaris) extract via MAPK/NF-κB signaling pathways and effects of digestive products on intestinal barrier and inflammation in Caco-2 and Raw264.7 co-culture

Li, Peng; Guo, Fanghua; Pei, Minjia; Tsao, Rong; Wang, Xiaoya; Jiang, Li; Sun, Yong; Xiong, Hua

doi:10.1016/j.jff.2022.105044

Public

Anti-inflammatory effect of lentil hull (Lens culinaris) extract via MAPK/NF-κB signaling pathways and effects of digestive products on intestinal barrier and inflammation in Caco-2 and Raw264.7 co-culture

Shared by NobleBlocks on Apr 1, 2022 • 12:00 AM UTC

Authors:

Peng Li

Fanghua Guo

Minjia Pei

Abstract

The polyphenol-rich lentil hulls are the by-product of lentils hulling process. In this manuscript, in vitro digestion, Caco-2 cell monolayer and Caco-2/RAW264.7 cell co-culture model were established to explore their anti-inflammatory mechanism, absorption of digestive products (RLD), and impact on...

Subject

Polyphenol

Caco-2

MAPK/ERK pathway

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!