Increased Incidence of Cytomegalovirus Disease After Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation

Holmberg, Leona; Boeckh, Michael; Hooper, Heather; M. Leisenring, Wendy; D. Rowley, Scott; Heimfeld, Shelly; W. Press, Oliver; G. Maloney, David; A. McSweeney, Peter; Corey, Lawrence; T. Maziarz, Richard; R. Appelbaum, Frederick; Bensinger, William

doi:10.1182/blood.v94.12.4029.424k21_4029_4035

Public

Increased Incidence of Cytomegalovirus Disease After Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation

Shared by NobleBlocks on Dec 15, 1999 • 12:00 AM UTC

Authors:

Leona Holmberg

Michael Boeckh

Heather Hooper

Abstract

High-dose therapy with autologous peripheral blood stem cell (PBSC) rescue is widely used for the treatment of malignant disease. CD34 selection of PBSC has been applied as a means of reducing contamination of the graft. Although CD34 selection results in a 2 to 3 log reduction in contaminating tumo...

Subject

Medicine

CD34

Transplantation

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