Oral pre-exposure prophylaxis (PrEP) to prevent HIV: a systematic review and meta-analysis of clinical effectiveness, safety, adherence and risk compensation in all populations

Ó Murchú, Éamon; E. Marshall, Liam; Teljeur, Conor; Harrington, Patricia; Hayes, Catherine; Moran, Patrick; Ryan, Máirín

doi:10.1136/bmjopen-2020-048478

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Oral pre-exposure prophylaxis (PrEP) to prevent HIV: a systematic review and meta-analysis of clinical effectiveness, safety, adherence and risk compensation in all populations

Published in BMJ Open • May 1, 2022

Authors:

Éamon Ó Murchú

Liam E. Marshall

Conor Teljeur

Abstract

OBJECTIVE: To conduct a systematic review and meta-analysis of randomised controlled trials (RCTs) of the effectiveness and safety of oral pre-exposure prophylaxis (PrEP) to prevent HIV. METHODS: Databases (PubMed, Embase and the Cochrane Register of Controlled Trials) were searched up to 5 July 202...

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Open Access

Subject

Medicine

Emtricitabine

Pre-exposure prophylaxis

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