Genetic regulation of the human plasma proteome in 54,306 UK Biobank participants

B. Sun, Benjamin; Chiou, Joshua; Traylor, Matthew; Benner, Christian; Hsu, Yi‐Hsiang; G. Richardson, Tom; Surendran, Praveen; Mahajan, Anubha; Robins, Chloe; G. Grinnell, Steven; Hou, Liping; Kvikstad, Erika; S. Burren, Oliver; Cule, Madeleine; Davitte, Jonathan; Ferber, Kyle; E. Gillies, Christopher; K. Hedman, Åsa; Hu, Sile; Lin, Tin-Chi; Mikkilineni, Rajesh; A. Pendergrass, Sarah; Pickering, Corran; P. Prins, Bram; Raj, Anil; Robinson, Jamie; Sethi, Anurag; D. Ward, Lucas; Welsh, Samantha; M. Willis, Carissa; Human Genetics, Alnylam; Genomics Initiative, AstraZeneca; Biobank Team, Biogen; Myers Squibb, Bristol; Human Genetics, Genentech; Genomic Sciences, GlaxoSmithKline; Integrative Biology, Pfizer; Analytics of Janssen Data Sciences, Population; Burkitt-Gray, Lucy; Helen Black, Mary; B. Fauman, Eric; M. M. Howson, Joanna; Min Kang, Hyun; I. McCarthy, Mark; Melamud, Eugene; Nioi, Paul; Petrovski, Slavé; A. Scott, Robert; N. Smith, Erin; Szalma, Sándor

doi:10.1101/2022.06.17.496443

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Genetic regulation of the human plasma proteome in 54,306 UK Biobank participants

Published in bioRxiv (Cold Spring Harbor Laboratory) • Jun 18, 2022

Authors:

Benjamin B. Sun

Joshua Chiou

Matthew Traylor

Abstract

Abstract The UK Biobank Pharma Proteomics Project (UKB-PPP) is a collaboration between the UK Biobank (UKB) and thirteen biopharmaceutical companies characterising the plasma proteomic profiles of 54,306 UKB participants. Here, we describe results from the first phase of UKB-PPP, including protein q...

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Open Access

Subject

Biobank

Biology

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