The FUS/circEZH2/KLF5/ feedback loop contributes to CXCR4-induced liver metastasis of breast cancer by enhancing epithelial-mesenchymal transition

Liu, Peng; Wang, Zehao; Ou, Xueqi; Wu, Peng; Zhang, Yue; Wu, Song; Xiao, Xiangsheng; Li, Yuehua; Ye, Feng; Tang, Hailin

doi:10.1186/s12943-022-01653-2

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The FUS/circEZH2/KLF5/ feedback loop contributes to CXCR4-induced liver metastasis of breast cancer by enhancing epithelial-mesenchymal transition

Shared by NobleBlocks on Oct 12, 2022 • 12:00 AM UTC

Authors:

Peng Liu

Zehao Wang

Xueqi Ou

Abstract

Abstract Background Metastasis of breast cancer have caused the majority of cancer-related death worldwide. The circRNAs are associated with tumorigenesis and metastasis in breast cancer according to recent research. However, the biological mechanism of circRNAs in liver metastatic breast cancer rem...

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