STEM-03. MOLECULAR PROFILING OF PRIMARY VERSUS RECURRENT GLIOBLASTOMA BRAIN TUMOR STEM CELLS UNCOVERS SIGNALING MECHANISMS THAT PROMOTE THE AGGRESSIVENESS OF RECURRENT GLIOBLASTOMA

Heemskerk, Kyle; Hao, Xiaoguang; Cseh, Orsolya; Artee Luchman, H.; Weiss, Samuel

doi:10.1093/neuonc/noac209.120

Public

STEM-03. MOLECULAR PROFILING OF PRIMARY VERSUS RECURRENT GLIOBLASTOMA BRAIN TUMOR STEM CELLS UNCOVERS SIGNALING MECHANISMS THAT PROMOTE THE AGGRESSIVENESS OF RECURRENT GLIOBLASTOMA

Shared by NobleBlocks on Nov 1, 2022 • 12:00 AM UTC

Authors:

Kyle Heemskerk

Xiaoguang Hao

Orsolya Cseh

Abstract

Abstract Glioblastoma (GBM) is a devastating brain cancer with a median overall survival of a mere 12-15 months. Patients receive the standard of care treatment, comprised of maximum surgical resection, ionizing radiation, and temozolomide chemotherapy, however the tumor inevitably recurs. Recurrent...

Subject

Stem cell

Temozolomide

Cancer research

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